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Study record managers: refer to the Data Element Definitions if submitting registration or information. To establish a National Clinical Trials Network NCTN mechanism for genomically screening large but homogeneous cancer populations and subsequently asing and accruing simultaneously to a multi-sub-study? Master Protocol.? To evaluate the screen success rate defined as the percentage of screened patients that register for a therapeutic sub-study. To evaluate if there is sufficient evidence to continue to the Rtc III component of the sub-study by comparing investigator-assessed progression-free survival IA-PFS between investigational therapy versus standard therapy SoC in patients with advanced stage refractory squamous cell carcinoma SCCA of the lung.

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